Dr McNally is the course leader for the BSc Microbiology degree course and the MSc Molecular Microbiology course. He is responsible for teaching aspects of molecular microbiology and microbial genomics / genetics across all levels.
Dr Mcnally is a member of the Pathogen Research Group
His research interests include:
- Microbial genomics: Perform all analysis of genome sequence data, including genome assembly, annotation, alignments, SNP typing and phylogenetics
- Yersinia Enterocolitica pathogenesis and evolution: Genome based studies of evolution of pathogenesis and translation of data to understanding the pathogenesis of this species complex
- Genomics of health care E.coli infections: Genome level investigation of bacteraemia and urine infections caused by E.coli, using genomics to track transmission and emergence of outbreaks.
Current research staff:
- Miquette Hall, PhD Studentship, Phylogenetics of the Yersinia genus, Year 2
- Fahad Alhashash, PhD Studentship, Molecular epidemiology of urosepsis, Year 2
- Alya Redhwan, PhD Studentship, Characterization of a novel TTSS in Yersinia, Year 2
- Dhahi Alenizi, PhD Studentship, Comparitive virulence strategies of Y.enterocolitica biotypes, Year 2
- Aziz Alqasim, PhD Studentship, Determining fitness traits of E.coli ST131, Year 2
- Andy Frey, Research Assistant, imaging E.coli ST131 infections
Completed PhD Students:
- Sandra Reuter, Evolution of the Yersinia genus, completed November 2011, currently PDRA at Wellcome Trust Sanger Institute
- Gemma Clark nee Croxall, Causative agents of polymicrobial UTI, complete December 2011, currently in Clinical Scientist Training Programme at Nottingham University Hospitals Trust.
Opportunities to carry out postgraduate research towards an MPhil / PhD or MSc by research exist in all the areas identified above. Further information may be obtained from the NTU Graduate School
Selected Publications
- Evolutionary dynamics of the yersinia enterocolitica complex. Reuter S, Thomson N R, McNally A, Adv Exp Med Biol, 2012, 954, 15-22
- Cj1136 is required for LOS biosynthesis, hyperinvasion and chick colonization by Campylobacter jejuni. Javed M A, Cawthraw S, Baig A, Li J, McNally A, Oldfield N, Newell D, Manning G, Infect Immun., 2012, 80, 2361-70
- Genomic analysis uncovers a phenotypically diverse but genetically homogenous Escherichia coli ST131 clone circulating in unrelated urinary tract infections. Clark G, Paszkieiwcz K, Hale J, weston V, Constantinidou C, Penn C W, Achtman M, McNally A, J Antimicrob Chemother, 2012, 67, 868-77
- Molecular epidermology of extra-intestinal pathogebic E.coli isolates from a regional cohort of elderly patients highlights prevalence of ST131 strains containing increased antimicrobal resistance in both community and hospital care settings. Croxall G, hale J, Weston V, Manning G, Cheetham P, Achtman M, McNally A, J Antimicrob Chemother, 2011, 66, 2501-8
- Pathogenesis of Escherichia coli from polymicrobial urinary tract infections. Croxall G, McNally A, J Med Microbiology, 2011, 60, 1554-5
- Increased human pathogenic potential of bacterial isolates from polymicrobial urinary tract infections in comparison to isolates from pure culture samples. Croxall G, Weston V, Joseph S, Manning G, Cheetham P, McNally A, J Med Microbiol, 2011, 60, 102-109
- Infection dynamics of highly pathogenic avian influenza and virulent avian paramyxovirus type 1 viruses in chickens, turkeys and ducks. Aldous EW, Seekings JM, McNally A, Nili H, Fuller CM, Irivine RM, ALexander DJ, Brown IH, Avain Pathology, 2010, 39 (4), 265-273
- Development of rapid, automated diagnostics for infectious disease: advances and challenges. Ince J and McNally A, Exp.Revs.Med.Devs, 2009, 6, 641-651
For full list click 'Go to Alan McNallys publications' link above
