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Mathematical Sciences Research Seminar

Investigating novel treatments for bacterial infections with mathematical models

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Seminars

As part of the School of Science and Technology Mathematical Sciences Research Centre Seminar Series, Dr Sara Jabbari, University of Birmingham presents: Investigating novel treatments for bacterial infections with mathematical models

  • From: Wednesday 6 December 2017, 1 pm
  • To: Wednesday 6 December 2017, 2 pm
  • Location: 169, New Hall Block, Nottingham Trent University, Clifton Campus, Clifton Lane, Nottingham, NG11 8NS
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Event details

As part of the School of Science and Technology Mathematical Sciences Research Centre Seminar Series, Dr Sara Jabbari, University of Birmingham presents: Investigating novel treatments for bacterial infections with mathematical models.

Abstract

The ability of bacteria to become resistant to previously successful antibiotic treatments is an urgent and increasing worldwide problem. Solutions can be sought via a number of methods including, for example, identifying novel antibiotics, re-engineering existing antibiotics or developing alternative treatment methods. The nonlinear interactions involved in infection and treatment render it difficult to predict the success of any of these methods without the use of computational tools in addition to more traditional experimental work. We use mathematical modelling to aid in the development of anti-virulence treatments that, unlike conventional antibiotics that directly target a bacterium’s survival, may instead attenuate bacteria and prevent them from being able to cause infection. Using examples such as anti-adhesion treatments for P. aeruginosa infections, we use ordinary differential equation modelling to predict both the success of anti-virulence treatments and also their drawbacks, drawing on the mathematical analyses to predict how the latter can be overcome.

This seminar is hosted by Dr David Chappell.

All welcome.

Location details

Room/Building:

169, New Hall Block

Address:

Nottingham Trent University
Clifton Campus
Clifton Lane
 Nottingham
 NG11 8NS

Past event

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