Chemistry and Forensic Science Colloquium
Mathematical modeling of topical/transdermal drug delivery
As part of the School of Science and Technology Chemistry and Forensic Science Colloquium Dr Yuri Anissimov, Griffith University (Australia) presents: Mathematical modeling of topical/transdermal drug delivery.
- From: Wednesday 25 April 2018, 1 pm
- To: Wednesday 25 April 2018, 2 pm
- Location: 193, Erasmus Darwin, Nottingham Trent University, Clifton Campus, Clifton Lane, Nottingham, NG11 8NS
Event details
As part of the School of Science and Technology Chemistry and Forensic Science Colloquium Dr Yuri Anissimov, Griffith University (Australia) presents: Mathematical modeling of topical/transdermal drug delivery.
Abstract
Transdermal drug delivery is a convenient route of drug administration, but is not without challenges. These challenges can be understood and sometimes addressed using mathematical modelling. Two aspects of mathematical modelling are essential in understanding topical drug delivery: 1. Predicting in-vivo and in-vitro penetration using physicochemical properties of drugs and 2. Using mathematical models to describe the rate of penetration following different topical applications and consequent drug distribution in different skin layers. In discussing prediction of penetration using physicochemical properties of solutes the emphasis will be on using maximum flux as a predictor of percutaneous drug penetration, as opposed to using a permeability coefficient common in the skin penetration literature. The potential of applying relatively simple compartmental approach in mathematical modelling of percutaneous drug delivery will be discussed as a response to increasing complexity in modelling drug penetration and distribution.
This seminar is hosted by Dr Dmitry Volodkin
For any queries please contact Dr Sophie Benjamin.
Location details
Room/Building:
Address:
Clifton Campus
Clifton Lane
Nottingham
NG11 8NS
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