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Biomedical Sciences Research Seminar Series

Overcoming addiction in bacteria: plasmid stability in pathogenic E. coli

Atomic structure of a biological molecule
Seminars

As part of the School of Science and Technology Biomedical Sciences Research Centre Seminar Series, Gareth McVicker, Nottingham Trent University presents: Overcoming addiction in bacteria: plasmid stability in pathogenic E. coli.

  • From: Wednesday 26 February 2020, 1.10 pm
  • To: Wednesday 26 February 2020, 2 pm
  • Location: ERD 282, Erasmus Darwin, Nottingham Trent University, Clifton Campus, Clifton Lane, Nottingham, NG11 8NS
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Event details

As part of the School of Science and Technology Biomedical Sciences Research Centre Seminar Series, Gareth McVicker, Nottingham Trent University presents: Overcoming addiction in bacteria: plasmid stability in pathogenic E. coli.

Abstract

Mobile genetic elements such as plasmids and viruses form an important part of the bacterial arsenal. As carriers of genes between different strains and species, they are responsible for the spread of both antibiotic resistance and virulence factors that can increase the severity of disease or worsen treatment outcomes. However, they often come with a cost to the bacterial cell, such as reduced growth rate. To ensure their persistence within a bacterial population, many plasmids encode toxin-antitoxin “addiction” systems that prevent their degradation or loss. In the McVicker lab we study a range of toxin-antitoxin systems in E. coli and related enteric bacteria in order to gain novel insights into the evolution and treatment of these extremely adaptable, and often highly pathogenic, organisms.

Hosted by Dr Jody Winter

All welcome.

For any enquiries please contact Dr Amanda Coutts

Location details

Room/Building:

ERD 282, Erasmus Darwin

Address:

Nottingham Trent University
Clifton Campus
Clifton Lane
Nottingham
NG11 8NS

Past event

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