Alan McNally

Alan Mcnally

Reader

School of Science & Technology

Staff Group(s)
Bioscience

Role

Dr McNally is a Reader in Microbial Genomics who leads an active research group studying the evolution and genomic epidemiology of microbial pathogens. He also teaches molecular microbiology and bioinformatics to BSc and MSc students.

Research areas

Dr Mcnally is a member of the Pathogen Research Group

His research interests include:

  • Microbial genomics: Perform all analysis of genome sequence data, including genome assembly, annotation, alignments, SNP typing and phylogenetics
  • Yersinia Enterocolitica pathogenesis and evolution: Genome based studies of evolution of pathogenesis and translation of data to understanding the pathogenesis of this species complex
  • Genomics of health care E.coli infections: Genome level investigation of bacteraemia and urine infections caused by E.coli, using genomics to track transmission and emergence of outbreaks.

Current research staff:

  • Ruqaiah Bedaiwi, PhD studentship, within host diversity of UPEC
  • Steven Dunn, PhD studentship, Genomic epidemiology of Campylobacter
  • Tristan Sreecharan, PhD studentship, inferring microbial ecology from phylogenetic data.

Opportunities to carry out postgraduate research towards an MPhil / PhD exist in all the areas identified above. Further information may be obtained from the NTU Graduate School.

External activity

  • Elected committee member of the Society for General Microbiology
  • Reviewer of articles for Nature Genetics, Microbiology, Journal of Medical Microbiology, Journal of Clinical Microbiology, Applied and Environmental Microbiology, Clinical Microbiology and infection, PLOS One, Environmental Microbiology, BMC Microbiology
  • Reviewer of grant applications for NIHR, MRC, BBSRC
  • Organiser of one-day EU meeting Rapid Diagnostics and Influenza, Paris, March 2011
  • Co-founder and chair of the East Midlands Infectious Diseases Research Network (2011- present)
  • Presenter of regular health headlines slot on BBC Radio Nottingham

Sponsors and collaborators

Current and recent research is being conducted with the collaboration, funding and / or support of:

Evolution of Bacterial Pathogenesis:

  • Prof Brendan Wren. London School of Hygiene and Tropical Medicine
  • Prof Nick Thomson. Sanger Centre
  • Prof Mike Prentice, University College Cork
  • Prof Jukka Corander, University of Helsinki
  • Prof Petra Desrch, HZI Braunschweig
  • Dr Steve Diggle, University of Nottingham
  • Dr Georgina Manning and Prof Steve Forsythe, Nottingham Trent University
    Medical Microbiology
  • Dr Mathew Diggle, Prof Vivienne Weston Queens Medical Centre Nottingham

Recent research funding includes:

  • Developing rapid diagnostics for influenza. EU FP7, (£67,000)
  • Developing rapid diagnostics for MRSA. C. difficile, Salmonella and Campylobacter (£208,000)
  • Countess Dowager Peel funded studies on determining causative agents of polymicrobial UTI in elderly patients (£75,000 studentship)
  • Genome sequencing project on Y. enterocolitica of all biotypes (£75,000 studentship)
  • NIHR funded work on biosensor based detection systems for infection control (£53,000)
  • EMDA funded project on link between urinary tract and sepsis E. coli (£56,000)

Publications

Selected Publications

For full list click 'Go to Alan McNallys publications' link above

See all of Alan McNally's publications...

Press expertise

Dr McNally can offer comment on the following:

  • Antimicrobial resistance in bacteria
  • E.coli infections
  • How bacteria evolve into human pathogens