Quentin Hanley

Quentin Hanley

Reader

School of Science & Technology

Staff Group(s)
Chemistry and Forensic Science

Role

Dr Hanley is a Reader in Analytical Chemistry and Head of Analytical Chemistry.

Career overview

- Lecturer/Senior Lecturer of Bioanalytical Chemistry at the University of the West Indies Cave Hill

- Scientist/PDRA Max Planck Institute for Biophysical Chemistry
- Research Assistant/Technician roles in Department of Environmental Health, University of Washington and Woods Hole Oceanographic Institution;
- Other Roles: Oil Refinery Chemist, Nuclear Reactor Operator/Senior Reactor Operator; Paper Test Technician.

Research areas

Areas of research interest include:

  • Fluctuation Scaling
  • Assay Format Design and development
  • Induced Assembly
  • Protein Aggregate Enumeration
  • Chemical Education
  • Multiplexing
  • Analytical Spectroscopy and Fluorescence Lifetime Imaging
  • Fluorescence Lifetime and Anisotropy Imaging
  • Analytical Spectroscopy
  • Fluorescence Microscopy
  • Fourier and Hadamard Transform Methods
  • Laue Diffraction

A wide range of other related topics in the general area of analytical spectroscopy and applied biophysics are also of interest. Current and previous research encompasses diagnostic assays with fluorescence methods, applications of fluorescence lifetime and anisotropy to biological problems and plasma membrane receptors, multi-step energy transfer techniques, the statistical behaviour of large data sets and scaling problems in a wide range of disciplines (chemical analysis, crime, property, and health).

Former PhD Students:

  • Dr Kathryn Murray (Currently University of Nottingham)
  • Dr Homanaz Ghafari (Currently University of Teheran)
  • Dr Zahra Gholami
  • Dr Zahra Zolmajd (Currently University of Teheran)

Current PhD Students:

  • Mr Marcin Fiedziukiewicz

Former MPhil Students:

  • Mr William Gumbs

Opportunities to carry out research towards an MPhil / PhD exist in all the areas identified above and further information may be obtained from the NTU Graduate School

External activity

Chair, Middle England Regional Chemistry Interactive Alliance (MERCIA)

Member of:

Judge, Organiser, or Co-organiser of East Midlands heats of the RSC Schools’ Analyst Competition (2006-2012).

Sponsors and collaborators

Current and recent research has being conducted with the collaboration, funding and / or support of:

Research funding in the period since 2006 includes:

  • NanoActuation of plasma membrane protein clusters, Q Hanley (NTU PI), EPSRC (2009 to 2012), £207,495. Part of a larger consortium including groups in the Netherlands and Germany.
  • Science and networking: building collaborative links between NTU and LICR and Monash University, Q Hanley (PI), EPSRC (2009), £6,115.
  • Imaging fluorescence from cells in 5 dimensions: X, Y, wavelength, lifetime and anistropy, Q Hanley (PI) and J Dickinson (CI), EPSRC (2007 to 2008), £115,424.
  • Multiparameter sensing for high sensitivity diagnostics using florescent and magnetic nanoparticles, Q Hanley (NTU PI), EU FP6 (2006 to 2009), €421,068. Part of a larger consortium including groups in Germany, the Netherlands, and Spain.

Publications

Chemical measurement and fluctuation scaling. Hanley QS, Analytical Chemistry, 2016, 88 (24), 12036-12042

Rural to urban population density scaling of crime and property transactions in English and Welsh Parliamentary Constituencies. Hanley QS, Lewis D and Ribiero HV, PLos One, 2016, 11 (2), e-0149546

When R > 0.8 R0: The Effects of Non-additivity, Distance, and Homo-FRET on Intensity and Anisotropy. Zolmajd-Haghighi Z, Hanley QS, Methods and Applications in Fluorenscence, 2016, 4:024006

The Nature of the Silicaphilic Fluorescence of PDMPO. Parambath M, Hanley Q, Martin-Martinez FJ, Giesa T, Buehler MJ and Perry C, Physical Chemistry Chemical Physics, 2016, 18, 5938-5948

Controlled Assembly of SNAP-PNA-Fluorophore systems on DNA Templates to Produce Fluorescence Resonance Energy Transfer. Gholami Z and Hanley Q, Bioconjugate Chemistry, 2014, 25, 1820-1828

Fluctuation scaling, Taylor's Law, and crime. Hanley QS, Khatun S, Yosef A, and Dyer RM, PLos One, 2014, 9 (10), e109004

PNA-induced assembly of fluorescent proteins using DNA as a framework. Gholami Z, Brunsveld L and Hanley Q, Bioconjugate Chemistry, 2013, 24 (8), 1378

Analysis of layered assays and volume microarrays in stratified media. Ghafari H and Hanley QS, Analyst, 2012, 137, 5520

Macromolecular binding and kinetic analysis with optically sectioned planar format assays. Ghafari H, Parambath M and Hanley QS, Analyst, 2012, 137, 4809

Lanthanide doped silica nanoparticles applied to multiplexed immunoassays. Murray K, Cao YC, Ali S and Hanley QS, Analyst, 2010, 135 (8), 2132-2138

Imaging lifetime and anisotropy spectra in the frequency domain. Zhou Y. Dickenson J, Hanley QS, Journal of Microscopy, 2009, 234 (1), 80-88

Confocal detection of planar homogeneous and heterogeneous immunosorbent assays. Ghafari H. Zhou Y, Ali S, Hanley QS, Journal of Biomedical Optics, 2009, 14 (6), 4022

Spectrally resolved frequency domain analysis of multi-fluorophore systems undergoing energy transfer. Forde TS and Hanley QS, Applied Spectroscopy, 2006, 60 (12), 1442-1452

See all of Quentin Hanley's publications...