Steve Allin

Steve Allin

Professor

School of Science & Technology

Staff Group(s)
Chemistry and Forensic Science

Role

Steve is a Professor of Organic Chemistry at Nottingham Trent University (part-time).

Career overview

Professor Allin studied Chemistry and Pharmacology at the University of Liverpool, being awarded a First Class honours degree in 1990 and his PhD in 1993.

Following postdoctoral studies at the University of Florida with Professor Alan R. Katritzky (FRS) he returned to the UK in 1995 as a Lecturer at the University of Huddersfield. He moved to Loughborough University in 1997, was promoted there to a Readership in 2005, and in 2008 was appointed to the Chair of Organic Chemistry at Keele University.

He joined NTU as the Head of Chemistry and Forensics in 2012 and then served from 2015-2017 as Head of the NTU Doctoral School, before taking up his current roles.

Professor Allin has supervised over 35 PhD students and has published widely in the peer-reviewed literature. His research has received funding in excess of £2.5 million from various sources including Research Councils, Charities and the Pharmaceutical Industry.

As a Founding Director of Charnwood Molecular Ltd, Professor Allin also has experience of the successful commercialisation of University research. Charnwood Molecular Ltd is a leading UK-based contract research organisation, with research sites in Loughborough and BioCity Nottingham, providing drug discovery and process research services to the global biotech and pharmaceutical sectors.

Research areas

Areas of research interest include:

  • organic synthesis and natural products
  • medicinal chemistry and drug discovery
  • drug delivery

Professor Allin has been involved in the supervision of over 35 PhD and postdoctoral researchers. Much of Professor Allin's current research work is collaborative in nature and he has particular interests in:

  • the development of novel anti-malarial agents (with Dr. Mike Edwards (Chemistry) and Dr. Paul Horrocks (Biochemistry), Keele University)
  • new drugs and drug delivery systems for the treatment of ovarian cancer (with Dr Alan Richardson, School of Pharmacy, Keele)
  • the area of asymmetric heterocyclic chemistry, and collaborates in materials chemistry (with Prof. John Wallis) and on anti-cancer projects (with Dr. Amanda Coutts) at NTU

Opportunities to carry out postgraduate research towards an MPhil / PhD exist in all the areas identified above. Further information may be obtained from the NTU Graduate School.

External activity

  • Managing Director, Charnwood Molecular Ltd
  • EPSRC College Member (Chemistry)
  • Fine Chemicals Group Committee Member (SCI)

Sponsors and collaborators

Current and recent research is being conducted with the collaboration, funding and / or support of:

University collaborations include University of East Anglia (Professor Phil Page), Keele University (Dr Paul Horrocks, Dr Alan Richardson and Dr Mark Skidmore) and Loughborough University (Dr Mark Elsegood, Professor Roger Mortimer).

Research funding in the period since 2005 includes:

  • MRC Industrial Case studentship, co-investigator with Mark Skidmore, Keele, (2012-2016)
  • MRC Industrial Case studentship, co-investigator with Alan Richardson, Keele, (2011-2015)
  • BBSRC Industrial Case studentship, co-investigator with Phil Page, UEA, (2011-2015)
  • North Staffs. Medical Institute, co-investigator with Paul Horrocks, Keele, (2009-2011)
  • EPSRC, (2008-2011)
  • Leverhulme Trust, co-investigator with Prof. Roger Mortimer, Dr. Mark Elsegood, Loughborough, (2008-2010)
  • EPSRC Industrial CASE studentship, Charnwood Molecular Ltd, (2007-2010)
  • EPSRC Industrial CASE studentship, Charnwood Molecular Ltd, (2007-2010)
  • EPSRC Engineering Doctorate studentship, Loughborough University, (2005-2009).

Publications

A dendrimer conjugate of 4-(tetradecanoylamino)benzyl]phosphonic acid (S32826) as an autotaxin inhibitor. Fisher N, Hilton-Bolt T, Edwards MG, Haxton K, McKenzie M, Allin SM and Richardson A, Medicinal Chemistry Letters, 2014, 5 (1), 34-39

Kinetic resolution in asymmetric epoxidation using iminium salt catalysis Bulman Page P, Appleby L, Chan Y, Day D, Buckley B, Slawin A, Allin SM, McKenzie M, Journal of Organic Chemistry 2013, 78, 8074

Application of a dual fries-claisen protocol to access pyranonaphthoquinone natural products. Duffy LJ, Garcia-Torres JR, Jones CF and Allin SM, Synlett, 2013, 185

Synthesis and evaluation of a novel series of indoloisoquinolines as small molecule anti-malarial leads. Horrocks P,  Fallon S, Denman L, Devine O, Duffy LJ, Harper A, Meredith EL, Hasenkamp S, Sidaway, D,  Phillips MT and Allin SM, Bioorganic and Medicinal Chemistry Letters, 2012, 22, 1770-1773

Enantioselective total synthesis of (+)-scuteflorin A using organocatalytic asymmetric epoxidation. Bartlett CJ, Chan Y,  Day D, Allin SM, Mckenzie MJ, Slawin AMZ and Bulman PC, Page, Journal of Organic Chemistry, 2012, 77, 772-774

Asymmetric epoxidation using iminium salt organocatalysts featuring dynamically controlled atropoisomerism. Bulman Page PC, Bartlett CJ, Chan Y, Day D, Parker P, Buckley BR, Rassias GA, Slawin AMZ, Allin SM, Lacour J and Pinto A, The Journal of Organic Chemistry, 2012, 77 (14), 6128

Development of a dual fries-claisen rearrangement strategy for benzannelation. Duffy LJ, Garcia-Torres J, Jones RCF,  Elsegood MRJ and Allin SM, Synlett, 2012, 1821

Asymmetric Synthesis of Benzo[a]quinolizidine Targets. Allin SM, Gaskell SN, Elsegood MRJ and Martin WP, Journal of Organic Chemistry, 2008, 73, 6448

See all of Steve Allin's publications...