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Cheuk-Wing LI

Cheuk-Wing Li

Lecturer/Senior Lecturer

School of Science & Technology


Dr Li is the Module Leader for Advanced Chemistry and Forensic Chemistry.  He teaches on the following modules

CHEM10191 Intro to Analytical Chemistry

CHEM10211 Intro to Forensic Analysis

CHEM20551 Analytical Chemistry

CHEM30310 Advanced Chemistry

CHEM30306 Advanced Chemical Analysis

CHEM19001 Chemistry Yr1 Tutorial Module

CHEM29001 Chemistry Yr2 Tutorial Module

Research areas

Dr. Li has been working in the field of biochip technology for over 17 years.  His research interests are focused on the development of low-cost biochip fabrication methods and the application of biochip technology in cell-based assays and high-throughput drug screening using microorganisms such as zebrafishes.


  1. Yu, G. D.; Lee, S. M. Y.; Li, C.-W.* "Studying the Time Course of Cardiac Responses of the Same Zebrafish using Scalable Fish-dock Microarchitecture" Sensors & Actuators: B. Chemical (2018) 268, 245-254.
  2. Ma, J.; Li, C.-W.* "Rapid and Continuous Parametric Screening for the Synthesis of Gold Nanocrystals with Different Morphologies by a Microfluidic Device" Sensors & Actuators: B. Chemical (2018) 262, 236-244.
  3. Gu, L.J.; Yu, G.D.; Li, C.-W.* "A Fast and Low-cost Microfabrication Approach for Six Types of Thermoplastic Substrates with Reduced Feature Size and Minimized Bulges using Sacrificial Layer Assisted Laser Engraving" Analytica Chimica Acta (2018) v997, 24-34.
  4. Li, L; Liu,Z; Zhang, H; Yue, W; Li, C.-W.* ; Yi, C. Q.* "A point-of-need enzyme linked aptamer assay for Mycobacterium tuberculosis detection using a smartphone" Sensors & Actuators: B. Chemical (2018) 254C, 337-346.
  5. M. K. Alam; E. Koomson; H. Zou; C.Q. Yi; Li C.-W. ; T. Xu; M.S. Yang "Recent advances in microfluidic technology for manipulation and analysis of biological cells (2007-2017)" Analytica Chimica Acta (2018) DOI:10.1016/j.aca.2018.06.054
  6. Li, C.-W.* ; Zhu, Y.; Zhan, J.S.; Ma, J.; Gu, L.; Fang, Y.; Yi, C. Q.* "Separation of Polystyrene Nanoparticles in Polydimethylsiloxane Microfluidic Devices with a Combined Titania and Sodium Dodecyl Sulfate Inner Coating" Microchimica Acta (2017), 184(7), 2227-2239.
  7. Ma, J.; Lee, S. M. Y.; Yi, C. Q.*; Li, C.-W.* "Controllable Synthesis of Functional Nanoparticles by Microfluidic Platform for Biomedical Applications - A Review" Lab On A Chip (2017),17, 209-226
  8. Yi Pan, Shi, Y. P.; Chen, J.; Wong, C. M.; Zhang, H.; Li, M. J.; Li, C.-W.* ,Yi, C. Q.* "Grafting Polyethylenimine with Quinoline Derivatives for Targeted Imaging of Intracellular Zn2+ and Logic Gate Operations" Materials Science & Engineering C-Materials for Biological Applications (2016), 69, 561-568.
  9. Pan, Y.; Shi, Y. P.; Chen, J.; Chen J.; Hou, M.; Chen, Z. P.; Li, C.-W. , Yi, C. Q.* "Design of Multiple Logic Gates Based on Chemically Triggered Fluorescence Switching of Functionalized Polyethylenimine" ACS Applied Materials & Interfaces (2016), 8, 9472-9482
  10. Ma, J.; Dong, H.*; Zhu, H. Y.; Li, C.-W. , Li, Y. Y.*; Shi, D. "Deposition of gadolinium onto the shell structure of micelles for integrated magnetic resonance imaging and robust drug delivery systems" Journal of Materials Chemistry B (2016), 4, 6094-6102.
  11. Yi, C. Q.; Liu, L.; Li, C.-W. ; Zhang, J.C.; Yang, M. S.* "Synthesis, characterization and biomedical application of multifunctional luminomagnetic core–shell nanoparticles" Materials Science & Engineering C-Materials for Biological Applications (2015), 46, 32-40
  12. Jiang, J. Y.; Zhan, J. S.; Yue, W. Q.; Yang, M. S.; Yi, C. Q.*; Li, C.-W.* "A Single Low-cost Microfabrication Approach for Polymethylmethacrylate, Polystyrene, Polycarbonate and Polysulfone Based Microdevices" RSC Advances. (2015), 5, 36036-36043
  13. Shi, Y. P.; Chen, Z. H.; Cheng, X.; Pan, Y.; Zhang, H.; Zhang, Z. M.; Li, C.-W. ; Yi, C. Q.*: A novel dual-emission ratiometric fluorescent nanoprobe for sensing and intracellular imaging of Zn2+. Biosensors & Bioelectronics (2014), 61, 397-403.
  14. Li, C.-W. *; Yu, G. D.; Jiang, J. Y.; Lee, S. M. Y.; Yi, C. Q.; Yue, W. Q.; Yang, M. S.: A microfluidic linear node array for the study of protein-ligand interactions. Lab On A Chip (2014), 14, 3993-3999.
  15. Yue, W. Q.; Zou, H.; Jin, Q. H.; Li, C.-W.; Xu, T.; Fu, H. Y.; Tzang, L. C. H.; Sun, H. Y.; Zhao, J. L.; Yang, M. S.*: Single layer linear array of microbeads for multiplexed analysis of DNA and proteins. Biosensors & Bioelectronics (2014), 54, 297-305.
  16. Chong, C. M.; Shen, M. Y.; Zhou, Z. Y.; Pan, P. C.; Hoi, P. M.; Li, S.; Liang, W.; Ai, N. N.; Zhang, L. Q.; Li, C.-W. ; Yu, H. D.; Hou, T. J.; Lee, S. M. Y.*: Discovery of a benzofuran derivative (MBPTA) as a novel ROCK inhibitor that protects against MPP+-induced oxidative stress and cell death in SH-SY5Y cells. Free Radical Biology and Medicine (2014), 74, 283-293.
  17. Xu T.; Yue, W.Q.; Li, C.-W. ; Yao, X. S.; Yang, M. S.* "Microfluidics study of intracellular calcium response to mechanical stimulation on single suspension cells" Lab On A Chip (2013), 13, 1060-1069.
  18. Li, C.-W. §; Yue, W. Q.§; (§ equal contribution) Xu, T.; Yang, M. S.* “Screen printing of solder resist as master substrates for fabrication of multi-level microfluidic channels and flask-shaped microstructures for cell-based applications” Biosensors & Bioelectronics (2013), 41, 675-683.
  19. Zhang, H.§; Lian, L.§; (§ equal contribution) Li, C.-W. ; Fu, H. Y.; Chen, Y.; Yang, M. S.* "Multienzyme-nanoparticles Amplification for Sensitive Virus Genotyping in Microfluidic Microbeads Array Using Au Nanoparticle Probes and Quantum Dots as Labels" Biosensors & Bioelectronics (2011), 29, 89-96
  20. Li, C.-W. §; Yue, W. Q.§;(§ equal contribution) Xu, T.; Yang, M. S.* “Integrated sieving microstructures on microchannels for biological cell trapping and droplet formation” Lab On A Chip (2011), 11, 3352-3355
  21. Chueh, B.-H.; Li, C.-W. ; Wu. H.; Davsion, M.; Wei, H. B.; Bhaya, D.; Zare, R. N.* “Whole gene amplification and protein separation from a few cells” Analytical Biochemistry (2011), 411, 64-70.
  22. Wei, H. B.; Chueh, B. H.; Wu, H. L.; Hall, E. W.; Li, C.-W. ; Schirhagl, R.; Lin, J.-M.; Zare, R. N.* "Particle Sorting Using a Porous Membrane in a Microfluidic Device" Lab On A Chip (2011), 11, 238-245.
  23. Li, M.-J.*, Jiao, P. C., He, W. W., Yi, C. Q., Li, C.-W. , Chen, X., Chen G.-N.*, Yang M. S. "Water-soluble and Biocompatible Cyclometalated Iridium(III) Complexes: Synthesis, Luminescence and Sensing Application" European Journal of Inorganic Chemistry (2011), 2, 197-200.
  24. Huang W.-D.; Zhang, H.; Xu, T.; Li, C.-W. ; Zhou L.-J.*; Yang, M. S.* “Separation of blood plasma by inertial focusing using microfluidic chips” Science Bulletin (2011), 56(21) 1711-1719
  25. Xu, T.; Yue, W. Q.; Li, C.-W. ; Yao, X. S.; Cai, G. P.; Yang, M. S.* “Real-time monitoring of suspension cell-cell communication using an integrated microfluidics” Lab On A Chip (2010), 10, 2271-2278.
  26. Yi, C. Q.; Li, C.-W. ; Zhang, M. L.; Wong, N. B.; Lee, S. T.; Yang, M. S.* “Patterned growth of vertically aligned silicon nanowire arrays for label-free DNA detection using surface-enhanced Raman spectroscopy” Analytical and Bioanalytical Chemistry (2010), 397(7), 3143-3150.
  27. Zhang, H.; Xu, T.; Li, C.-W. ; Yang, M. S.* "A microfluidic device with microbead array for sensitive virus detection and genotyping using quantum dots as fluorescence labels" Biosensors & Bioelectronics (2010), 25, 2402-2407.
  28. Xu, T.; Li, C.-W. ; Yao, X. S.; Cai, G. P.; Yang, M. S.* “Microfluidic formation of single cell array for parallel analysis of CRAC channel activation and inhibition” Analytical Biochemistry (2010), 396, 173-179.
  29. Li, C.-W. ; Yang, M. S.* “3-D Streamline Steering by Nodes Arrayed in Entangled Microfluidic Network” Lab On A Chip (2007), 7, 1712-1716.
  30. Li, C.-W. ; Chen, R. S.; Yang, M. S.* “Generation of linear and non-linear concentration gradients along microfluidic channel by microtunnel controlled stepwise addition of sample solution” Lab On A Chip (2007), 7, 1371-1373.
  31. Yang, M. S.*; Tsoi, P. Y.; Li, C.-W. ; Zhao, J.-L. “Analysis of Interactions of Template/primer Duplexes with T7 DNA Polymerase by Oligonucleotide Microarray” Sensors & Actuators: B. Chemical (2006), 115(1), 428-433.
  32. Yi, C. Q.; Zhang, Q.; Li, C.-W. ; Yang, J.; Zhao, J.-L.; Yang, M. S.* “Optical and Electrochemical Detection Techniques for Cell-based Microfluidic Systems” Analytical and Bioanalytical Chemistry (2006), 384, 1259-1268.
  33. Yi, C. Q.; Li, C.-W. ; Jin, S. L.; Yang, M. S.* “Microfluidics Technology for Manipulation and Analysis of Biological Cells” Analytica Chimica Acta (2006), 560, 1-23.
  34. Li, C.-W. ; Yang, J.; Tzang, C. H.; Zhao, J.-L.; Yang, M. S.* “Using Thermally Printed Transparency as Photomasks to Generate Microfluidic Structures in PDMS Material” Sensors & Actuators: A. Physical (2006), 126, 463-468.
  35. Li, C.-W. ; Yang, J.; Yang, M. S.* “Dose-dependent Cell-based Assays in V-shaped Microfluidic Channels” Lab On A Chip (2006), 6, 921-929.
  36. Yang, M. S.*; Tsoi, P. Y.; Li, C.-W. ; Woo, S. H.; Zhao, J.-L.; Yam, W. C. “Detection of Mutations in RNA Polymerase Beta Subunit Gene Encoding Resistance to Rifampin in Mycobacterium Tuberculosis by DNA Microarray” Analytical Letters (2005), 38(13), 2117-2134.
  37. Tzang, C. H.; Li, C.-W. ; Zhao, J.-L.; Yang, M. S.*; “Electrocatalytic Phenol Oxidation on Mixed Pt-RuO2 Nanoparticle Modified Electrode” Analytical Letters (2005), 38(11), 1735-1746.
  38. Yang, J.; Li, C.-W. ; Yang, M. S.* “Hydrodynamic Simulation of Cell Docking in Microfluidic Channels with Different Dam Structures” Lab On A Chip (2004), 4(1), 53-59.
  39. Li, C.-W. ; Cheung, C. N.; Yang, J.; Tzang, C. H.; Yang, M. S.* “PDMS-based Microfluidic Device with Multi-height Structures Fabricated by Single-step Photolithography using Printed Circuit Board as Masters” Analyst (2003), 128(9), 1137-1142.
  40. Yang, J.; Li, C.-W. ; Yang, M. S.* “Lab-on-a-chip (Microfluidics) technology” Acta Biochimica Et Biophysica Sinica (2002), 34(2), 117-123.
  41. Yang, M. S.*; Li, C.-W. ; Yang, J. “Cell Docking and On-chip Monitoring of Cellular Reactions with Controlled Concentration Gradient on a Microfluidic Device” Analytical Chemistry (2002), 74(16), 3991-4001.
  42. Yang, M. S.*; Yang, J.; Li, C.-W. ; Zhao, J.-L. “Generation of Concentration Gradient by Diffusive mixing and Consecutive Dilution in a Microfluidic Chip” Lab On A Chip (2002), 2(3), 158-163.