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Nadia Chuzhanova

Nadia Chuzhanova


School of Science & Technology

Staff Group(s)
Physics and Mathematics


Professor Nadia Chuzhanova is a Professor of Biomedical Mathematics. She is involved in teaching Probability & Statistical Inference at undergraduate level and Research Methodology & Ethics, Computational Statistics & Data Analysis and Statistical Data Analysis modules at postgraduate level. She also supervises PhD students and the final year projects in Statistics/Mathematics and Bioinformatics.

Career overview

  • Reader in Bioinformatics and a Head of Bioinformatics, Biophysics and Self-Organising Systems cluster at The University of Central Lancashire, Preston (2006-2010)
  • Research Fellow, Lecturer, Head of Bioinformatics at Cardiff University (1998-2006)

Research areas

Professor Chuzhanova is a member of the Biomathematics and Bioinformatics research group.

Research group blog.

Areas of research interest include Bioinformatics of mutagenesis with the aim of developing novel mathematical, statistical and computational methods and algorithms for identification of specific DNA sequence features, epigenetic factors and other architectural features that mediate and drive mutagenesis both in pathology and evolution.

Professor Chuzhanova is particularly interested in developing approaches for predicting remotely acting regulatory elements and in understanding their role in disease developments and progression. Using data on 3D architecture of the human genome her group has predicted novel remotely-acting regulatory elements for the NF1 and SMCHD1 genes mutated in patients with neurofibromatosis type 1 and facioscapulohumeral dystrophy, respectively. This approach was further extended to the studies of single nucleotide polymorphisms found to associate with schizophrenia and longevity in Drosophila by genome-wide association studies with the aim of finding novel genes and genomic regions linked to genetic disorders or longevity.

Opportunities arise to carry out postgraduate research towards an MPhil / PhD in the areas identified above. Further information may be obtained on the NTU Research Degrees website

Current and recent postgraduate supervisory experience

PhD students

  • Bethany Hall (submitted) In silico modelling of longevity of Drosophila melanogaster: a network approach
  • Anahita Bayani (in progress) Modelling anti-inflammatory systems through cellular automata
  • Amelia Padmore (in progress) Multiplex network models of the brain
  • Rebecca Martin (completed 2018) Collocation techniques for solving neural field models on complex cortical geometries
  • Daniel Buxton (completed 2017) Remotely acting mutations in genetic disease and cancer: features and properties
  • Nicole Pearcy (completed 2015) Unravelling the complexity of metabolic networks
  • Mihir Kamat (completed 2015) The involvement of non-B DNA forming sequences in mediating missense muattions, micro-deletions and micro-insertions in human inherited disease
  • Dobril Ivanov (completed 2009) Comparative analysis of germline and somatic microlesion mutational spectra in 17 human tumour suppressor genes
  • Edward Ball (completed 2004) Microdeletions and microinsertions causing human genetic disease

Recent MRes students:

  • Jack Sutton (completed 2018) Understanding the 3D architecture of the Drosophila genome
  • Suliman Mohammad Suliman Almansour (completed 2019) Identification of cancer subtypes using similarity network fusion of diverse types of genome-wide data

External activity

Professor Chuzhanova is a member of the ESRC DTC/DTP Peer Review College.

Sponsors and collaborators

Current and recent research is being conducted with the collaboration, funding and/or support of:

University collaborations include:


Selected publications

See all of Nadia Chuzhanova's publications...