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Ian Varley

Ian Varley

Associate Professor

School of Science & Technology

Staff Group(s)
Sport

Role

Ian teaches Exercise Physiology on undergraduate, (Sport and Exercise Science, Coaching and Sport Science, Exercise Nutrition and Health, Sport Science and Management) and postgraduate courses (MRes Exercise Physiology). This involves being Module Leader on the Illness and Injury in Sport and Exercise module and contributing to other modules across all degree programs.

Career overview

Ian is an Associate Professor at Nottingham Trent University. Ian authored 25+ peer-reviewed publications. These include 4* publications in world leading journals such as Nature communications (Impact factor 12.1), Sports Medicine (Impact factor 9.8) and Science translational medicine (Impact factor 16.3). Ian has presented at numerous prestigious Sport Science related conferences (American College of Sports Medicine, European College of Sport Science) and presented to leading sporting governing bodies (English Institute of Sport, The English Cricket board, The Football Association, The Premier League, The Women’s Super League).

Ian's main research interests are; Injury and Illness Surveillance, The impact of exercise and physical activity on stress related bone injury, bone structure and bone metabolism and Genetic associations with alterations in bone structure and injury. Ian has experience in leading consultancy based activities related to Injury and Illness for various sporting bodies, including The Football Association and the Premier League.

Research areas

Ian's research interests are:

  • Injury and Illness Surveillance
  • The impact of exercise and physical activity on stress related bone injury, bone structure and bone metabolism.
  • Genetic associations with alterations in bone structure and injury.

External activity

  • Experience in leading consultancy based activities related to Injury and Illness for various sporting bodies, including The Football Association and the Premier League.

Sponsors and collaborators

Current and recent research is being conducted with the collaboration and/or support of:

  • Dr Craig Sale- Manchester Met University
  • Dr Charlotte Cowie - The Football Association  
  • Dr Rene Best - Barbados Military
  • Dr Julie Greeves-Army Training and Recruitment Division

Publications

VARLEY, I., JAMES, L.J., WILLIS, S.A., KING, J.A. and CLAYTON, D.J., 2022. One week of high-fat overfeeding alters bone metabolism in healthy males: a pilot study. Nutrition, 96: 111589. ISSN 0899-9007

BORDOLI, C., MURPHY, E., VARLEY, I., SHARPE, G. and HENNIS, P., 2022. A systematic review investigating the effectiveness of exercise training in glycogen storage diseases. Therapeutic Advances in Rare Disease, 3. ISSN 2633-0040

MODE, W.J.A., SMALL, C., JOHNS, S., SLATER, T., HOUGH, J., VARLEY, I., JAMES, R.M., JAMES, L.J. and CLAYTON, D.J., 2021. The acute effects of morning and evening fasting on energy intake, appetite and glycaemic control in young, healthy males. Appetite: 105577. ISSN 0195-6663

MCAULEY, A.B.T., HUGHES, D.C., TSAPROUNI, L.G., VARLEY, I., SURACI, B., ROOS, T.R., HERBERT, A.J. and KELLY, A.L., 2021. Genetic testing in professional football: perspectives of key stakeholders. Journal of Science in Sport and Exercise. ISSN 2096-6709

TEMPLEMAN, I., SMITH, H., CHOWDHURY, E., CHEN, Y.C., CARROLL, H., JOHNSON-BONSON, D., HENGIST, A., SMITH, R., CREIGHTON, J., CLAYTON, D., VARLEY, I., KARAGOUNIS, L.G., WILHELMSEN, A., TSINTZAS, K., REEVES, S., WALHIN, J.P., GONZALEZ, J.T., THOMPSON, D. and BETTS, J.A., 2021. A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults. Science Translational Medicine, 13 (598): eabd8034. ISSN 1946-6234

CIVIL, R., BROOK, M.S., ELLIOTT‐SALE, K.J., SANTOS, L., VARLEY, I., LENSU, S., KAINULAINEN, H., KOCH, L.G., BRITTON, S.L., WILKINSON, D.J., SMITH, K., SALE, C. and ATHERTON, P.J., 2021. A collagen extraction and deuterium oxide stable isotope tracer method for the quantification of bone collagen synthesis rates in vivo. Physiological Reports, 9 (10): e14799. ISSN 2051-817X

VARLEY, I., STEBBINGS, G., WILLIAMS, A.G., DAY, S., HENNIS, P., SCOTT, R., GRAZETTE, N. and HERBERT, A.J., 2021. An investigation into the association of bone characteristics and body composition with stress fracture in athletes. Journal of Sports Medicine and Physical Fitness. ISSN 0022-4707 (Forthcoming)

MARTIN, D., TIMMINS, K., COWIE, C., ALTY, J., MEHTA, R., TANG, A. and VARLEY, I., 2021. Injury incidence across the menstrual cycle in international footballers. Frontiers in Sports and Active Living, 3: 616999. ISSN 2624-9367

SPROUSE, B., ALTY, J., KEMP, S., COWIE, C., MEHTA, R., TANG, A., MORRIS, J., COOPER, S. and VARLEY, I., 2020. The Football Association Injury and Illness Surveillance Study: the incidence, burden and severity of injuries and illness in men’s and women’s international football. Sports Medicine. ISSN 0112-1642

MCAULEY, A.B.T., HUGHES, D.C., TSAPROUNI, L.G., VARLEY, I., SURACI, B., ROOS, T.R., HERBERT, A.J. and KELLY, A.L., 2020. The association of the ACTN3 R577X and ACE I/D polymorphisms with athlete status in football: a systematic review and meta-analysis. Journal of Sports Sciences. ISSN 0264-0414

MCAULEY, A.B.T., HUGHES, D.C., TSAPROUNI, L.G., VARLEY, I., SURACI, B., ROOS, T.R., HERBERT, A.J. and KELLY, A.L., 2020. Genetic association research in football: a systematic review. European Journal of Sport Science. ISSN 1746-1391

DOLAN, E., VARLEY, I., ACKERMAN, K.E., PEREIRA, R.M.R., ELLIOTT-SALE, K.J. and SALE, C., 2020. The bone metabolic response to exercise and nutrition. Exercise and Sport Sciences Reviews, 48 (2), pp. 49-58. ISSN 0091-6331

CLAYTON, D.J., JAMES, L.J., SALE, C., TEMPLEMAN, I., BETTS, J.A. and VARLEY, I., 2020. Severely restricting energy intake for 24 h does not affect markers of bone metabolism at rest or in response to re-feeding. European Journal of Nutrition. ISSN 1436-6207

PATEL, S. and VARLEY, I., 2019. Exploring the regulation of genetic testing in sport. Entertainment and Sports Law Journal, 17 (1): 5. ISSN 1748-944X

VARLEY, I., GREEVES, J. and SALE, C., 2019. Seasonal difference in bone characteristics and body composition of elite speed skaters. International Journal of Sports Medicine, 40 (01), pp. 9-15. ISSN 0172-4622

VARLEY, I., HUGHES, D.C., GREEVES, J.P., STELLINGWERFF, T., RANSON, C., FRASER, W.D. and SALE, C., 2018. The association of novel polymorphisms with stress fracture injury in elite athletes: further insights from the SFEA cohort. Journal of Science and Medicine in Sport, 21 (6), pp. 564-568. ISSN 1440-2440

VARLEY, I., HUGHES, D.C., GREEVES, J.P., FRASER, W.D. and SALE, C., 2018. SNPs in the vicinity of P2X7R, RANK/RANKL/OPG and Wnt signalling pathways and their association with bone phenotypes in academy footballers. Bone, 108, pp. 179-185. ISSN 8756-3282

VARLEY, I., PATEL, S., WILLIAMS, A.G. and HENNIS, P.J., 2018. The current use, and opinions of elite athletes and support staff in relation to genetic testing in elite sport within the UK. Biology of Sport, 35, pp. 13-19. ISSN 0860-021X

VARLEY, I., LEWIN, R., NEEDHAM, R., THORPE, R.T. and BURBEARY, R., 2017. Association between match activity variables, measures of fatigue and neuromuscular performance capacity following elite competitive soccer matches. Journal of Human Kinetics, 60 (1), pp. 93-99. ISSN 1899-7562

WILLEMS, S.M., WRIGHT, D.J., DAY, F.R., TRAJANOSKA, K., JOSHI, P.K., MORRIS, J.A., MATTEINI, A.M., GARTON, F.C., GRARUP, N., OSKOLKOV, N., THALAMUTHU, A., MANGINO, M., LIU, J., DEMIRKAN, A., LEK, M., XU, L., WANG, G., OLDMEADOW, C., GAULTON, K.J., LOTTA, L.A., MIYAMOTO-MIKAMI, E., RIVAS, M.A., WHITE, T., LOH, P.-R., AADAHL, M., AMIN, N., ATTIA, J.R., AUSTIN, K., BENYAMIN, B., BRAGE, S., CHENG, Y.-C., CIĘSZCZYK, P., DERAVE, W., ERIKSSON, K.-F., EYNON, N., LINNEBERG, A., LUCIA, A., MASSIDDA, M., MITCHELL, B.D., MIYACHI, M., MURAKAMI, H., PADMANABHAN, S., PANDEY, A., PAPADIMITRIOU, I., RAJPAL, D.K., SALE, C., SCHNURR, T.M., SESSA, F., SHRINE, N., TOBIN, M.D., VARLEY, I., WAIN, L.V., WRAY, N.R., LINDGREN, C.M., MACARTHUR, D.G., WATERWORTH, D.M., MCCARTHY, M.I., PEDERSEN, O., KHAW, K.-T., KIEL, D.P., OEI, L., ZHENG, H.-F., FORGETTA, V., LEONG, A., AHMAD, O.S., LAURIN, C., MOKRY, L.E., ROSS, S., ELKS, C.E., BOWDEN, J., WARRINGTON, N.M., MURRAY, A., RUTH, K.S., TSILIDIS, K.K., MEDINA-GÓMEZ, C., ESTRADA, K., BIS, J.C., CHASMAN, D.I., DEMISSIE, S., ENNEMAN, A.W., HSU, Y.-H., INGVARSSON, T., KÄHÖNEN, M., KAMMERER, C., LACROIX, A.Z., LI, G., LIU, C.-T., LIU, Y., LORENTZON, M., MÄGI, R., MIHAILOV, E., MILANI, L., MOAYYERI, A., NIELSON, C.M., SHAM, P.C., SIGGEIRSDOTIR, K., SIGURDSSON, G., STEFANSSON, K., TROMPET, S., THORLEIFSSON, G., VANDENPUT, L., VAN DER VELDE, N., VIIKARI, J., XIAO, S.-M., ZHAO, J.H., EVANS, D.S., CUMMINGS, S.R., CAULEY, J., DUNCAN, E.L., DE GROOT, L.C.P.G.M., ESKO, T., GUDNASON, V., HARRIS, T.B., JACKSON, R.D., JUKEMA, J.W., IKRAM, A.M.A., KARASIK, D., KAPTOGE, S., KUNG, A.W.C., LEHTIMÄKI, T., LYYTIKÄINEN, L.-P., LIPS, P., LUBEN, R., METSPALU, A., VAN MEURS, J.B.J., MINSTER, R.L., ORWOLL, E., OEI, E., PSATY, B.M., RAITAKARI, O.T., RALSTON, S.W., RIDKER, P.M., ROBBINS, J.A., SMITH, A.V., STYRKARSDOTTIR, U., TRANAH, G.J., THORSTENSDOTTIR, U., UITTERLINDEN, A.G., ZMUDA, J., ZILLIKENS, M.C., NTZANI, E.E., EVANGELOU, E., IOANNIDIS, J.P.A., EVANS, D.M., OHLSSON, C., PITSILADIS, Y., FUKU, N., FRANKS, P.W., NORTH, K.N., VAN DUIJN, C.M., MATHER, K.A., HANSEN, T., HANSSON, O., SPECTOR, T., MURABITO, J.M., RICHARDS, J.B., RIVADENEIRA, F., LANGENBERG, C., PERRY, J.R.B., WAREHAM, N.J. and SCOTT, R.A., 2017. Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Nature Communications, 8, p. 16015. ISSN 2041-1723

VARLEY, I., HUGHES, D., GREEVES, J., FRASER, W. and SALE, C., 2017. Increased Training Volume Improves Bone Density and Cortical Area in Adolescent Football Players. International Journal of Sports Medicine. ISSN 0172-4622

VARLEY, I., GREEVES, J.P., SALE, C., FRIEDMAN, E., MORAN, D.S., YANOVICH, R., WILSON, P.J., GARTLAND, A., HUGHES, D.C., STELLINGWERFF, T., RANSON, C., FRASER, W.D. and GALLAGHER, J.A., 2016. Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury. Purinergic Signalling. ISSN 1573-9538

SALE, C., VARLEY, I., JONES, T.W., JAMES, R.M., TANG, J.C.Y., FRASER, W.D. and GREEVES, J.P., 2015. Effect of carbohydrate feeding on the bone metabolic response to running. Journal of Applied Physiology, 119 (7), pp. 824-830. ISSN 8750-7587

VARLEY, I., HUGHES, D.C., GREEVES, J.P., STELLINGWERFF, T., RANSON, C., FRASER, W.D. and SALE, C., 2015. RANK/RANKL/OPG pathway: genetic associations with stress fracture period prevalence in elite athletes. Bone, 71, pp. 131-136. ISSN 8756-3282

HALL, C., VARLEY, I., KAY, R. and CRUNDALL, D., 2014. Keeping your eye on the rail: gaze behaviour of horse riders approaching a jump. PLoS ONE, 9 (5). ISSN 1932-6203

See all of Ian Varley's publications...

Press expertise

  • Injury and illness surveillance
  • The influence of exercise on bone health
  • Bone health in athletes
  • The influence of genetics on injury/performance