Skip to content

Dr Jehan EL-Jawhari

Lecturer

Department of Biosciences, School of Science and Technology

Role

  • Lecturer (teaching and research) of Medical Biochemistry at Nottingham Trent University
  • Honorary research fellow at the University of Leeds

Research areas

Chronic diseases, degenerative and ageing-related disorders.

Immunology of tissue regeneration.

Cellular regenerative therapies.

Cancer Immunology.

Publications

The Biological Fitness of Bone Progenitor Cells in Reamer/Irrigator/Aspirator Waste.

El-Jawhari JJ, Ganguly P, Churchman S, Jones E, Giannoudis PV.

J Bone Joint Surg Am. 2019 Dec 4;101(23):2111-2119. doi: 10.2106/JBJS.19.00133.

PMID: 31800424

Defective Proliferation and Osteogenic Potential with Altered Immunoregulatory phenotype of Native Bone marrow-Multipotential Stromal Cells in Atrophic Fracture Non-Union.

El-Jawhari JJ, Kleftouris G, El-Sherbiny Y, Saleeb H, West RM, Jones E, Giannoudis PV.

Sci Rep. 2019 Nov 22;9(1):17340. doi: 10.1038/s41598-019-53927-3.

PMID: 31758052

The Analysis of In Vivo Aging in Human Bone Marrow Mesenchymal Stromal Cells Using Colony-Forming Unit-Fibroblast Assay and the CD45lowCD271+ Phenotype.

Ganguly P, El-Jawhari JJ, Burska AN, Ponchel F, Giannoudis PV, Jones EA.

Stem Cells Int. 2019 Aug 1;2019:5197983. doi: 10.1155/2019/5197983. eCollection 2019.

PMID:31467563

Gene expression and functional comparison between multipotential stromal cells from lateral and medial condyles of knee osteoarthritis patients.

Sanjurjo-Rodriguez C, Baboolal TG, Burska AN, Ponchel F, El-Jawhari JJ, Pandit H, McGonagle D, Jones E.

Sci Rep. 2019 Jun 27;9(1):9321. doi: 10.1038/s41598-019-45820-w.

PMID: 31249374

Identification of senescent cells in multipotent mesenchymal stromal cell cultures: Current methods and future directions.

Zhai W, Yong D, El-Jawhari JJ, Cuthbert R, McGonagle D, Win Naing M, Jones E.

Cytotherapy. 2019 Aug;21(8):803-819. doi: 10.1016/j.jcyt.2019.05.001. Epub 2019 May 25. Review.

PMID:31138507

A crosslinked collagen membrane versus a non-crosslinked bilayer collagen membrane for supporting osteogenic functions of human bone marrow-multipotent stromal cells.

El-Jawhari JJ, Moisley K, Jones E, Giannoudis PV.

Eur Cell Mater. 2019 Apr 24;37:292-309. doi: 10.22203/eCM.v037a18.

PMID:31016711

Optimising proliferation and migration of mesenchymal stem cells using platelet products: A rational approach to bone regeneration.

Moisley KM, El-Jawhari JJ, Owston H, Tronci G, Russell SJ, Jones EA, Giannoudis PV.

J Orthop Res. 2019 Jun;37(6):1329-1338. doi: 10.1002/jor.24261. Epub 2019 Mar 28. Erratum in: J Orthop Res. 2019 Sep;37(9):2061.

PMID:30816585

Novel methodology to discern predictors of remission and patterns of disease activity over time using rheumatoid arthritis clinical trials data.

RA-MAP Consortium .

RMD Open. 2018 Oct 25;4(2):e000721. doi: 10.1136/rmdopen-2018-000721. eCollection 2018.

PMID:30487994

T cell immunomodulation by clinically used allogeneic human cancellous bone fragments: a potential novel immunotherapy tool.

El-Sherbiny YM, El-Jawhari JJ, Moseley TA, McGonagle D, Jones E.

Sci Rep. 2018 Sep 10;8(1):13535. doi: 10.1038/s41598-018-31979-1.

PMID:30201960

Vertebral body versus iliac crest bone marrow as a source of multipotential stromal cells: Comparison of processing techniques, tri-lineage differentiation and application on a scaffold for spine fusion.

Fragkakis EM, El-Jawhari JJ, Dunsmuir RA, Millner PA, Rao AS, Henshaw KT, Pountos I, Jones E, Giannoudis PV.

PLoS One. 2018 May 24;13(5):e0197969. doi: 10.1371/journal.pone.0197969. eCollection 2018.

PMID:29795650

The regenerative therapies of the ankle degeneration: a focus on multipotential mesenchymal stromal cells.

El-Jawhari JJ, Brockett CL, Ktistakis I, Jones E, Giannoudis PV.

Regen Med. 2018 Mar 19. doi: 10.2217/rme-2017-0104. [Epub ahead of print]

PMID:29553890

Age-related Changes in Bone Marrow Mesenchymal Stromal Cells: A Potential Impact on Osteoporosis and Osteoarthritis Development.

Ganguly P, El-Jawhari JJ, Giannoudis PV, Burska AN, Ponchel F, Jones EA.

Cell Transplant. 2017 Sep;26(9):1520-1529. doi: 10.1177/0963689717721201. Review.

PMID:29113463

The CD45lowCD271high Cell Prevalence in Bone Marrow Samples May Provide a Useful Measurement of the Bone Marrow Quality for Cartilage and Bone Regenerative Therapy.

El-Jawhari JJ, Cuthbert R, McGonagle D, Jones E, Giannoudis PV.

J Bone Joint Surg Am. 2017 Aug 2;99(15):1305-1313. doi: 10.2106/JBJS.16.01138.

PMID:28763416

Interleukin-22 drives the proliferation, migration and osteogenic differentiation of mesenchymal stem cells: a novel cytokine that could contribute to new bone formation in spondyloarthropathies.

El-Zayadi AA, Jones EA, Churchman SM, Baboolal TG, Cuthbert RJ, El-Jawhari JJ, Badawy AM, Alase AA, El-Sherbiny YM, McGonagle D.

Rheumatology (Oxford). 2017 Mar 1;56(3):488-493. doi: 10.1093/rheumatology/kew384.

PMID:27940584

The roles of immune cells in bone healing; what we know, do not know and future perspectives.

El-Jawhari JJ, Jones E, Giannoudis PV.

Injury. 2016 Nov;47(11):2399-2406. doi: 10.1016/j.injury.2016.10.008. Review.

PMID:27809990

Collagen-containing scaffolds enhance attachment and proliferation of non-cultured bone marrow multipotential stromal cells.

El-Jawhari JJ, Sanjurjo-Rodríguez C, Jones E, Giannoudis PV.

J Orthop Res. 2016 Apr;34(4):597-606. doi: 10.1002/jor.23070. Epub 2015 Dec 1.

PMID:26466765

Modulation of peripheral T-cell function by interleukin-7 in rheumatoid arthritis.

Churchman SM, El-Jawhari JJ, Burska AN, Parmar R, Goëb V, Conaghan PG, Emery P, Ponchel F.

Arthritis Res Ther. 2014 Dec 23;16(6):511. doi: 10.1186/s13075-014-0511-3.

PMID:25533722

An immunological biomarker to predict MTX response in early RA.

Ponchel F, Goëb V, Parmar R, El-Sherbiny Y, Boissinot M, El Jawhari J, Burska A, Vital EM, Harrison S, Conaghan PG, Hensor E, Emery P.

Ann Rheum Dis. 2014 Nov;73(11):2047-53. doi: 10.1136/annrheumdis-2013-203566. Epub 2013 Aug 29.

PMID:23989988

Mesenchymal stem cells, autoimmunity and rheumatoid arthritis.

El-Jawhari JJ, El-Sherbiny YM, Jones EA, McGonagle D.

QJM. 2014 Jul;107(7):505-14. doi: 10.1093/qjmed/hcu033. Epub 2014 Feb 10. Review.

PMID:24518000

Blocking oncogenic RAS enhances tumour cell surface MHC class I expression but does not alter susceptibility to cytotoxic lymphocytes.

El-Jawhari JJ, El-Sherbiny YM, Scott GB, Morgan RS, Prestwich R, Bowles PA, Blair GE, Tanaka T, Rabbitts TH, Meade JL, Cook GP.

Mol Immunol. 2014 Apr;58(2):160-8. doi: 10.1016/j.molimm.2013.11.020. Epub 2013 Dec 22.

PMID:24365750

Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity.

Wilson EB, El-Jawhari JJ, Neilson AL, Hall GD, Melcher AA, Meade JL, Cook GP.

PLoS One. 2011;6(9):e22842. doi: 10.1371/journal.pone.0022842. Epub 2011 Sep 6.

PMID:21909397

Course(s) I teach on

  • Student using science lab
    Undergraduate | Full-time | 2020

    https://www.ntu.ac.uk/study-and-courses/courses/find-your-course/science-technology/ug/2020-21/bsc-biochemistry

  • Students in science lab
    Undergraduate | Full-time / Part-time / Sandwich | 2020

    https://www.ntu.ac.uk/study-and-courses/courses/find-your-course/science-technology/ug/2020-21/biological-sciences

  • Scientific experiement
    Postgraduate taught / Professional | Full-time / Part-time / Sandwich | 2020

    https://www.ntu.ac.uk/study-and-courses/courses/find-your-course/science-technology/pg/2020-21/molecular-cell-biology