Dr Bonner is Programme Leader for the MRes in Applied Biosciences.
Dr Bonner is a member of the Interdisciplinary Biomedical Sciences Centre, Protein Purification and Proteomics Research Group
Research Assistant / Technician:
- Mr Wayne Harris
- Mrs Imelda Borland
- Ibtesam Almami
- Maha Aldubayan
Dr P Bonner's primary area of research is transglutaminase, with research being undertaken in three key areas:
- The role of transglutaminase in plant tissue and the isolation of inhibitors of this enzyme from plant tissue
- The role of mammalian transglutaminases in brain and heart function
- The industrial uses of transglutaminases
Additional projects include the following:
- The use of Information Computer Technology (ICT) to support molecular sciences teaching is being developed to enhance student learning.
Dr Bonner has specific expertise in the fields of protein/peptide purification and enzymology.
Opportunities to carry out postgraduate research towards an MPhil/PhD by research exist in all the areas identified above. Further information may be obtained from the NTU Graduate School.
- Member of the Biochemistry Society
- External Examiner for Bournemouth University (Somerset, 2002-2006)
Sponsors and collaborators
Current and recent research is being conducted with the collaboration, funding and/or support of:
- The Higher Education Innovation Fund (HEIF)
University collaborations include Bologna and Derby.
Research funding in the period since 2002 includes:
- Enzyme Inhibitors, HEIF (2011), £16,000
- EEC Framework 5, Dr P Bonner and Dr A Hargreaves in collaboration with Professor P Lynch, University of Derby CRYMECEPT (2002 to 2005)
- Identification of MHC peptides, Professor R Rees, Professor C Creaser and Dr P Bonner, Kay Kendall Leukaemia Fund (2001 to 2004), £300,000
- Enzymes in the textile industry, Professor M Griffin and Dr P Bonner, BBRC (2001 to 2004), £150,000
- Novel Luciferase purification procedures, Lumitech UK (2001 to 2002), £30,000
- An extracellular transglutaminase is required for apple pollen tube growth. Di Sandro A, Del Duca S, Verderio E, Hargreaves AJ, Scarpellini A, Cai G, Cresti M, Faleri C, Iorio RA, Hirose S, Furantini Y, Coutts IG, Griffin M, Bonner PLR and Serafini-Fracassini D, Biochemical J, 2010, 429, 261-271
- Effects of chlorpyrifos on transglutaminase activity in differentiating rat C6 glioma cells. Muñoz D, Bonner PLR and Hargreaves AJ, Toxicology In Vitro, 2010, 24, 2104-2107
- Effects of post-translational modifications catalysed by pollen transglutaminase on the functional properties of microtubules and actin filaments. Del Duca S, Serafini-Fracassini D, Bonner PLR, Cresti M and Cai G, Biochemical J, 2009, 418, 651-664
- Estimation of peptide concentration by a modified bicinchoninic acid assay. Kapoor KN, Barry DT, Rees RC, Dodi IA, McArdle SEB, Creaser CS and Bonner PLR, Anal. Biochem. 2009, 393, 138-140
- Effects of phenyl saligenin phosphate on cell viability and transglutaminase activity in N2a neuroblastoma and HepG2 hepatoma cell lines. Harris W, Muñoz D, Bonner PLR and Hargreaves AJ, Toxicology In Vitro, 2009, 23, 1559-1563
For full list click 'Go to Philip Bonner's publications' link aboveSee all of Philip L R Bonner's publications...