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Centre

Centre for Systems Health and integrated Metabolic Research (SHiMR)

Research theme: Health and Wellbeing

School: School of Science and Technology

Overview

The Centre for Systems Health and Integrated Metabolic Research (SHiMR) harnesses cutting edge technological approaches to understand the common underpinning mechanisms of healthy resilience, and how this deteriorates during development of disease and ageing.

SHiMR unifies scientific excellence across four core research themes:

    • Metabolic Health
    • Neuroscience
    • Cancer Immunogenomics
    • Microbiology

We pursue discovery science to identify new potential therapeutic targets to address the global disease burdens of obesity, diabetes, neurodegenerative disease, cancer, and the burgeoning threat of anti-microbial resistance. Cancer research and its clinical translation are enhanced through co-localisation with the John van Geest Cancer Research Centre.

We invest in the most advanced scientific methodologies to deliver on our research mission, and have specialist technological capacity in imagingcellular energeticsspatial and multi-modal omics, computational biology and in vitro 3D– and in vivo preclinical modelling.

SHiMR forges regional, national and international partnerships, holds grants and PhD Programmes with leading academic institutions, disease-focussed charities and pharmaceutical companies, and actively seeks to expand our research with a global perspective.