Metabolic Health

Research within the Metabolic Health theme encompasses analysis of the molecular basis of genetic and cellular events that impact metabolic processes.

Our research is increasing our understanding of fundamental processes and identifying biomarkers and therapeutic interventions to target metabolic diseases including diabetes, obesity and cancer.

Our researchers have proven expertise and track record of success in the study of diet and lifestyle factors affecting metabolic health and pathology during early development, in specific disease states and in ageing.

The Metabolic Health group works at the interface of basic biological research, human translational research and bioengineering to increase understanding and provide new tools to combat diseases and improve health.

Our research and PhD opportunities

Opportunities often arise for postgraduate research towards a PhD within our research team. If you are interested in carrying out a PhD please contact the prospective supervisor directly or visit our Research Degrees webpage.

Current funded PhD opportunities:

• Identifying, mapping, and predicting resistance to β-lactam/β-lactamase inhibitor combinations
• The role of long non-coding RNA regulatory networks in pancreatic cancer
• 3D modelling of the bone marrow tumour microenvironment in pre-leukaemic disorders
• Defining the role of HIF1α in hypoxia induced chronic pain
• ADP-Ribosylation as a regulator of metabolism
• Exploiting pathogens for the treatment of clinical and veterinary infections
• Characterising the survival of microbial biofilms in drying river ecosystems
• Targeting CES1 to improve the treatment of aggressive colorectal carcinoma
• Investigating epilepsy associated tRNA fragments
• Brain regulation of obesity through appetite and metabolism